Over 70 years Vitamin D experience in The Netherlands

Application:
Alfacalcidol is a Vitamin D3 analog for the Pharmaceutical and Veterinary industry. Alfacalcidol is especially used to prevent and treat osteoporosis or decalcification of bones. The substance is also active against other bone growth disorders such as osteomalacia, rickets and specific liver and parathyroid glands abnormalities. It is also used for the treatment and prevention of secondary hyperparathyroidism associated with chronic kidney disease (CKD).

Specification:
Names: Alfacalcidol; 1α-hydroxycholecalciferol; 1α-hydroxyvitamin D3
Content Alfacalcidol (HPLC) is 97.0-102.0%

CAS: 41294-56-8

Regulatory: CEP/CoS and DMF available

Application:
Calcitriol is a Vitamin D3 analog for the Pharmaceutical and Veterinary industry. Calcitriol is especially used to prevent and treat osteoporosis or decalcification of bones. The substance is also active against other bone growth disorders such as osteomalacia, rickets and specific liver and parathyroid glands abnormalities. It is also used for the treatment and prevention of secondary hyperparathyroidism associated with chronic kidney disease (CKD).

Specification:
Names: Calcitriol; 1α,25-dihydroxycholecalciferol; 1α,25-dihydroxyvitamin D3; 1,25 DHCC
Content Calcitriol (HPLC) is 97.0-102.0%

CAS: 32222-06-3

Regulatory: CEP/CoS and DMF available

Application:
Calcifediol is a Vitamin D3 analog for the Pharmaceutical and Veterinary industry. Calcifediol is especially used to prevent and treat osteoporosis or decalcification of bones. The substance is also active against other bone growth disorders such as rickets, osteomalacia and specific liver and parathyroid glands abnormalities. It is also used for the treatment and prevention of secondary hyperparathyroidism associated with chronic kidney disease (CKD).

Specification:
Names: Calcifediol; 25-hydroxyvitamin D3;25-hydroxycholecalciferol; 25-HCC
Content Calcifediol (HPLC) is 97.0-102.0%

CAS: 63283-36-3 (monohydrate), 19356-17-3 (anhydrous)

Regulatory: CEP/CoS and DMF available

Application:
Ercalcidiol is an active Vitamin D2 analog for the Pharmaceutical industry. Ercalcidiol can be used for the treatment of disorders in Calcium and Phosphorhomeostasis. It can also be used as a marker for Vitamin D3 catabolism and a predictor of serum 25-hydroxycholecalciferol response to Vitamin D3 supplementation.

Specification:
Chemical name: Ercalcidiol; 25-hydroxyergocalciferol; 25-hydroxy D2
Content Ercalcidiol (HPLC) is ≥ 90%

CAS: 21343-40-8

Regulatory: Non-GMP material

Application:
Vitamin D2 is used to ensure the right concentration of calcium and phosphorus in the blood. Ergocalciferol is used to treat and prevent bone growth disorders such as osteomalacia, rickets and osteoporosis. Recent research shows that Vitamin D2 can also be of paramount importance to prevent other abnormalities and diseases as well. Several forms of cancer and auto-immune diseases are targeted by several research companies. Vitamin D2 can also be used as starting material for APIs.

Specification:
Names: Vitamin D2 pure; Ergocalciferol; Calciferol
Content Ergocalciferol is 97.0-102.0%; 1 gram is equivalent to 40,000,000 IU of Vitamin D2

CAS: 50-14-6

Regulatory: DMF available (an ASMF has been filed and accepted in several European countries)

Application:
Paricalcitol is an active Vitamin D2 analog for the Pharmaceutical industry. Paricalcitol is used for the treatment and prevention of secondary hyperparathyroidism associated with chronic kidney disease (CKD). It has been shown to reduce parathyroid hormone levels by inhibiting its synthesis and secretion.

Specification:
Names: Paricalcitol; 19-NOR-1α,25-dihydroxyergocalciferol; 19-NOR-1α,25-dihydroxy D2
Content Paricalcitol (HPLC) is 97.0-103.0%

CAS: 131918-61-1

Regulatory: DMF available (an ASMF has been filed and accepted in several European countries)

Application:
Secalciferol is an active Vitamin D analog for the Pharmaceutical industry. Secalciferol can be used for the treatment of disorders in Calcium and Phosphor homeostasis. It can also be used as a marker for Vitamin D3 catabolism and a predictor of serum 25-hydroxycholecalciferol response to Vitamin D3 supplementation.

Specification:
Names: Secalciferol; 24R,25-dihydroxycholecalciferol; 24R,25-dihydroxyvitamin D3; 24R 25 DHCC
Content Secalciferol (HPLC) is ≥ 95%

CAS: 55721-11-4

Regulatory: Non-GMP material