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CARBOGEN AMCIS Expands Operations in Switzerland

CARBOGEN AMCIS, the Swiss-based pharmaceutical process development and Active Pharmaceutical Ingredient (API) manufacturing company, has announced plans to take over operations of a high-containment facility located in Vionnaz, Switzerland, 70 kilometers East of Geneva:

CARBOGEN AMCIS │ Route du Simplon 24 │ CH-1895 Vionnaz │ Switzerland

The high potency facility in Vionnaz opened in December 2005 and was formerly managed by Bachem AG as an integrated part of their site in Vionnaz. Designed to operate at OEL < 0.1μg/m3 8h-TWA, the unit is cGMP-compliant and inspected by Swissmedic and by the U.S. Food and Drug Administration (FDA). Effective today, CARBOGEN AMCIS has signed an agreement to officially take over control of this unit. Operations are slated to start later this fall.

“We are facing a significant increase in the demand for high potency services, spurred by the fast-paced growth of the Antibody Drug Conjugates (ADCs) market. The expansion in Vionnaz will ensure we can continue to fulfill customer needs and expectations while our company continues to grow and expand.” commented Mark Griffiths, CEO CARBOGEN AMCIS. “Our partners will benefit from additional high potency capabilities available at the Vionnaz facility such as high potency laboratories, cGMP kilo-scale manufacturing, as well as larger scale lyophilisation.”

The Vionnaz unit is dedicated to the development and manufacture of highly potent APIs and can accommodate projects from gram to multi-kilo scale. The facility is completely independent and features a process development laboratory, a dedicated QC laboratory and two production units fitted with reactors up to 30 L, as well as a freeze dryer for lyophilisation and chromatography. Operations involving cytotoxic compounds are performed under containment conditions in line with CARBOGEN AMCIS’ standards of safety and quality. The building is self-contained and segregated from the outside. All laboratories from gram to kilo-scale production are cGMP compliant.

The substantial increase in development capabilities and manufacturing space for highly potent drugs in Vionnaz, along with the recent construction of a clean room dedicated to conjugation projects in Bubendorf, positions CARBOGEN AMCIS as industry leader and outsourcing partner for complex highly potent APIs and ADCs. In the near future, the company plans to introduce additional capability for highly potent drugs at the Neuland (Hunzenschwil) site to meet customer needs in chemical development and niche commercial manufacturing.


CARBOGEN AMCIS AG ( is a leading service provider, offering a portfolio of drug-development and commercialization services to the pharmaceutical and biopharmaceutical industry at all stages of drug development. The integrated services provide innovative chemistry solutions to support timely and safe drug development allowing customers to make the best use of available resources. CARBOGEN AMCIS AG is owned by Dishman Pharmaceuticals and Chemicals Ltd., Ahmedabad, India. 

Dishman Group ( is a global outsourcing partner for the pharmaceutical industry, offering a portfolio of development, scale-up and manufacturing services. Dishman Group improves its customers’ businesses by providing a range of development and manufacturing solutions at locations in Europe, China and India.