Case study: First Industrial (Total) Synthesis of Amanitin Derivatives by CARBOGEN AMCIS

In this full case study, you’ll find valuable insights into the synthesis approach and potential ADC applications.

Specifically, the case study covers:
•• A brief overview of the first total industrial synthesis of Amanitin derivatives entering Phase I & II clinical trials.
•• Insights into the unique properties and structural challenges of the molecule.
•• A detailed synthetic analysis of the approach and chemistry involved.
•• Information on the successful collaboration and contributions from various sites within our organization.

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Article written by Emad El Sayed, Ph.D.
Senior Manager PR&D at CARBOGEN AMCIS

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