ADC & Bioconjugation
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Antibody Drug Conjugates and Bioconjugation

As pioneers in the highly potent landscape for over 14 years, CARBOGEN AMCIS has successfully delivered a significant number of drug-linker projects. Our first Antibody Drug Conjugates (ADC) project was delivered in 2005. Since then, our customers, ranging from small biotech to large pharmaceutical companies, have taken full advantage of our ADC and bioconjugation capabilities.

Our state-of-the-art bioconjugation facility, staffed with a dedicated team of experts, has been in operation for several years and can support you in conceptualizing and delivering the best linker and conjugation strategy.

Our ADC suite is directly supported by both our small molecule development capabilities and our formulation expertise that provide an end-to-end solution, in order to rapidly progress your New Chemical Entities (NCE) in support of your goals.

It's exciting to have the opportunity to apply my knowledge of chemistry and biotechnology to contribute to the success of our customer’s bioconjugation projects. I work with a multinational and multi-disciplinary team who inspire me on a professional and personal level.

Elena - Senior Chemist ADC Analytics, Bubendorf

Why choose us?

Warheads

Drug-linker

cGMP process development and manufacture of Warheads & Linkers (OEL < 0.01 µg/m3)

Conjugation

Conjugation

cGMP Conjugation of mAb to Small

Molecules & Polymers

Dedicated Team

A multi-disciplinary and extensively experienced team

Clean Room

Clean Room

Clean Room fully qualified for cGMP manufacturing dedicated to bio-conjugation

Purification

Purification

State of art purification technologies

Analytical

Analytical

Outstanding analytical capabilities

Fill-&-Finish

Fill & Finish

Fill-&-Finish capabilities

Support

Support

Regulatory and CMC support

cGMP-Bioconjugation Suite

Personnel Airlock

 C -15Pa

Material Airlock

C -15 Pa

Material Airlock

D +30 Pa

Personnel Airlock

D +30 Pa

Grade D Clean Room

+15 Pa Pressure
Area for equipment storage and sanitisation, reagent and buffer preparation

Grade C Conjugation Suite

0 Pa Pressure
Grade C area for conjugation, purification, and packaging processes

Looking towards the personnel & material airlocks with space for reactors

Looking towards the mobile reactors & isolator

Looking towards the barrier & walk-in hoods, TFF

Looking towards the autoclave, hot-air steriliser, sample pass & material airlocks

Looking towards the analytical bench, barrier hood & personnel airlock

  • Personnel Airlock

     C -15Pa

  • Material Airlock

    C -15 Pa

  • Material Airlock

    D +30 Pa

  • Personnel Airlock

    D +30 Pa

  • Grade D Clean Room

    +15 Pa Pressure
    Area for equipment storage and sanitisation, reagent and buffer preparation

  • Grade C Conjugation Suite

    0 Pa Pressure
    Grade C area for conjugation, purification, and packaging processes

  • Looking towards the personnel & material airlocks with space for reactors

  • Looking towards the mobile reactors & isolator

  • Looking towards the barrier & walk-in hoods, TFF

  • Looking towards the autoclave, hot-air steriliser, sample pass & material airlocks

  • Looking towards the analytical bench, barrier hood & personnel airlock

Bioconjugates and Antibody Drug Conjugates

For more information
download our Bioconjugation & Antibody Drug Conjugates
brochure or contact us today.